Painful immune system disease Lupus is a disease that is characterized by the destruction of the immune system leading to inflammation in numerous places across the body. The most commonly affected regions are the kidney, the brain, the skin as well as different joints. There are different types of lupus, and perhaps the most common is SLE-Systemic Lupus Erythematosus. This is a devastating condition that causes the destruction of multiple organs. Patients suffering from this disease will have ...